Method for purifying 5′ -protected thymidines and novel derivatives thereof
US6875860B2 · kind B2 · utility
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8Claims
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Assignee
Inventors
Key dates
| Filing date | May 15, 2002 |
| Grant date | Apr 5, 2005 |
| Priority date | — |
| Expiry date | Sep 12, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H19/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention provides a method for efficiently purifying 5′-protected thymidines which cannot be efficiently purified by the prior art. Impurities can be separated by obtaining crystals including a carbonyl-containing solvent to provide a highly pure 5′-protected thymidine. Thus, this invention allows 5′-protected thymidines, which cannot be purified in an industrial scale by the prior art, to be easily provided with a high purity in a large scale.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.