Process for removing systematic error and outlier data and for estimating random error in chemical and biological assays
US6876929B2 · kind B2 · utility
Inventors
Key dates
| Filing date | Nov 8, 2001 |
| Grant date | Apr 5, 2005 |
| Priority date | — |
| Expiry date | Mar 24, 2022 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16B25/10
- WIPO fieldComputer technology
- WIPO sectorElectrical engineering
Abstract
A method for improving the reliability and/or accuracy of physical measurements obtained from array hybridization studies performed on an array having a large number of genomic samples uses a small number of replicates insufficient for making precise and valid statistical inferences. This is overcome by estimating an error in measurement of a sample by averaging errors obtained when measuring the large number of samples or a subset of the large number of samples. The estimated sample error is utilized as a standard for accepting or rejecting the measurement of the respective sample. The samples may be independent or dependent in that correlated across two or more conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.