Methods for the identification of compounds useful for the treatment of disease states mediated by prostaglandin D2
US6878522B2 · kind B2 · utility
6Cited by
1References
11Claims
0Family size
Inventors
Key dates
| Filing date | Apr 11, 2001 |
| Grant date | Apr 12, 2005 |
| Priority date | — |
| Expiry date | Dec 27, 2021 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/02
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to the discovery that PDG2 is the nautral ligand for orphan receptor CRTH2, which interaction, it will now immediately be recognized, is important in the development of valuable pharmaceuticals. The present invention is therefore related to methods for screening for therapeutic compounds useful in the treatment of PGD2-related disorders such as allergy, asthma and inflammation. Appropriate assay methodology is also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.