Fractionating apparatus having colonies of pillars arranged in migration passage at interval and process for fabricating pillars
US6881315B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 31, 2002 |
| Grant date | Apr 19, 2005 |
| Priority date | — |
| Expiry date | Jan 10, 2023 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2030/285
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A fractionating apparatus is used for fractionating sample into micro-structures different in size, and includes a fractionating unit formed with a fractionating passage; the fractionating passage is defined in a groove formed in a substrate of the fractionating unit, and pillar patches are formed in the groove at intervals wider than the gap among the pillar patches; while the sample is migrated through the fractionating passage, small-sized DNA molecules are trapped in the pillar patches, and large-sized DNA molecules are smoothly migrated through the wide intervals; this results in that the large-sized DNA molecules reaches the end of the fractionating passage faster than the small-sized DNA molecules without clogging.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.