Patent · US Expired

On chip dilution system

US6883957B2 · kind B2 · utility

11Cited by
19References
15Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 25, 2002
Grant dateApr 26, 2005
Priority date
Expiry dateOct 30, 2022

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10T436/25625
  • WIPO fieldChemical engineering
  • WIPO sectorChemistry

Abstract

An on-chip chemical compound dilution system for providing dilution of a chemical compound in a microfluidic application includes at least one sample well for providing a selected chemical compound to be diluted, a dilution well for providing a diluent for diluting the chemical compound, a network of channels for carrying the chemical compound and diluent, a first syringe pump for effecting dilution, a second syringe pump, a detector and a plurality of valves for selectively controlling the flow of liquid through the channels. The dilution system may be a multiple-stage dilution system for precisely mixing a plurality of chemical compounds in a diluent. The dilution system allows for accurate calibration to compensate for variations due to manufacturing, thereby providing precise dilution ratios. The dilution system further enables flushing to allow re-use of the system with another chemical compound.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.