Formulation of stabilized cationic transfection agent(s) /nucleic acid particles
US6884430B1 · kind B1 · utility
4Cited by
3References
35Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 9, 1999 |
| Grant date | Apr 26, 2005 |
| Priority date | — |
| Expiry date | Aug 9, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention concerns a composition containing stabilized particles of cationic transfection agents/nucleic acid complexes characterized in that it includes besides said transfection agent and nucleic acid at least a non-ionic surfactant in sufficient amount for preventing the aggregation of the particles in course of time. In a preferred embodiment, the surfactant is a polyoxyalkylene or a derivative thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.