Antitumoral composition based on immunogenic polypeptide with modified cell location
US6884786B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 17, 1998 |
| Grant date | Apr 26, 2005 |
| Priority date | — |
| Expiry date | Jul 17, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2710/20022
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Antitumoral compositions can comprise as therapeutic agent one or several immunogenic polypeptides, of which at least one is modified so as to have a cell location different from its native location. Compositions can be based on a recombinant vector expressing such an immunogenic polypeptide. A recombinant vector comprising at least the sequences coding for an immunogenic polypeptide originating from a precocious and/or tardive region of a papillomavirus having a modified location and a viral particle comprising the vector is also described. Finally, therapeutic uses of such a composition, such a recombinant vector and such a viral particle are described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.