Notch
US6887475B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | May 4, 1999 |
| Grant date | May 3, 2005 |
| Priority date | — |
| Expiry date | May 4, 2019 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S424/81
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to the use of therapeutic compounds in the modification of T-cells, T-cell-antigen presenting cell (APC) interactions and the interaction between pathogenic organism and immunocompetent cells of a host. In particular, it relates to the use of these compounds in the modulation of the interaction between Notch proteins and their ligands and to the use of such compounds in the therapy of conditions such as graft rejection, autoimmunity, allergy, asthma and infectious diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.