Modulating a pharmacokinetic property of a drug by administering a bifunctional molecule containing the drug
US6887842B1 · kind B1 · utility
20Cited by
11References
20Claims
0Family size
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Key dates
| Filing date | Nov 17, 2000 |
| Grant date | May 3, 2005 |
| Priority date | — |
| Expiry date | Oct 20, 2021 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/812
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Bifunctional molecules and methods for their use are provided. The subject bifunctional molecules are conjugates of a drug moiety and a pharmacokinetic modulating moiety, where these two moieties are optionally joined by a linking group. The bifunctional molecules are further characterized in that they exhibit at least one modulated pharmacokinetic property upon administration to a host as compared to a free drug control. The subject bifunctional molecules find use in a variety of therapeutic applications.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.