Compounds as dynamic organ function monitoring agents
US6887854B2 · kind B2 · utility
19Cited by
10References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 13, 2003 |
| Grant date | May 3, 2005 |
| Priority date | — |
| Expiry date | May 13, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D209/60
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Highly hydrophilic indole and benzoindole derivatives that absorb and fluoresce in the visible region of light are disclosed. These compounds are useful for physiological and organ function monitoring. Particularly, the molecules of the invention are useful for optical diagnosis of renal and cardiac diseases and for estimation of blood volume in vivo.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.