Reagent and method for measuring lung function
US6890305B2 · kind B2 · utility
5Cited by
5References
25Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 26, 2003 |
| Grant date | May 10, 2005 |
| Priority date | — |
| Expiry date | May 2, 2023 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K49/0004
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to an assay for evaluating alveolar exchange of oxygen. A 13C-labeled substrate, such as 13C-sodium bicarbonate is administered to a subject by oral or iv intake, and exhaled 13CO2 is measured. The 13CO2 in expired breath can be collected at various time points following administration of the substrate and measured in Δ per mil with a mass analyzer or photometer, such as an IR spectrometer. This process can be used as a diagnostic test for the indication of, treatment and/or evaluation of the severity of respiratory tract diseases or infections.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.