Kinesin inhibitors
US6890933B1 · kind B1 · utility
29Cited by
1References
19Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 23, 2001 |
| Grant date | May 10, 2005 |
| Priority date | — |
| Expiry date | Feb 23, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides for compounds, compositions, methods and systems for inhibiting cell growth. More specifically, the present invention provides for methods, compounds and compositions which are capable of inhibiting mitosis in metabolically active cells. Compounds, compositions and methods of the present invention inhibit the activity of a protein involved in the assembly and maintenance of the mitotic spindle. One class of proteins which acts on the mitotic spindle is the family of mitotic kinesins, a subset of the kinesin superfamily.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.