Lapachone delivery systems, compositions and uses related thereto
US6890950B2 · kind B2 · utility
41Cited by
2References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 23, 2003 |
| Grant date | May 10, 2005 |
| Priority date | — |
| Expiry date | Jun 5, 2023 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB82Y5/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
In part, the present invention is directed to a system comprising a lapachone or a prodrug thereof and a polymer, such as a biocompatible and optionally biodegradable polymer, methods for treatment using the subject polymer compositions, and methods of making and using the same. In another part, the present invention includes inclusion complexes of a lapachone or a prodrug thereof and a cyclodextrin, preferably a β-cyclodextrin, such as hydroxypropyl β-cyclodextrin, e.g., to improve the solubility of the lapachone or prodrug thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.