Aryloxypropanolamine derivatives, method of preparation and applications thereof
US6890955B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 3, 2003 |
| Grant date | May 10, 2005 |
| Priority date | — |
| Expiry date | Jan 3, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D317/66
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention concerns aryloxypropanolamine derivatives having at least an anti-diabetic and anti-fat activity and their methods of preparation and applications, particularly as human and veterinary medicine and animal food additive. These derivatives comply with the general formula (I) in which R2 represents one of the following groups: —CH2—, —CH2—CH2, —CH(CH3)—CH2—, —C(CH3)═CH—, —C(CH3)2—CH2— or a bond; Q represents: (i) a phenyl radical 3,4-disubstituted alkylene dioxy determining with the phenyl radical, a non-substituted benzodioxane unit, a non-substituted benzodioxol unit, or a 2-substituted benzodioxol unit, (ii) a phenyl radical 3 and/or 4-substituted, by a O—(CH2)x—COOR5 group, (iii) a condensed polycyclic hydrocarbon comprising at least two condensed cycles, (iv) a cyclic hydrocarbon system, optionally cross-linked, and constituting a cycloalkane comprising 1, 2 or 3 cycles
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.