Labelling compounds for the simple synthesis of 3'-[18F]fluoro-3'-deoxythymidine and a method for the production thereof

US6891033B2 · kind B2 · utility

Assignee

• DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES ÖFFENTLICHEN RECHTS · DE

Inventors

• Stefan Johannes Martin · Dossenheim, DE
• Joseph Antonius Maria Eisenbarth · Ketsch, DE
• Ulrike Wagner-Utermann · Heppenheim, DE
• Michael Eisenhut · Heidelberg, DE
• Walter Mier · Bensheim, DE

Key dates

• Filing date: Jan 28, 2002
• Grant date: May 10, 2005
• Expiry date: Jan 28, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07H19/06
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The application relates to compounds that are suitable as labelable precursors for synthesis of 3′-[18F]fluoro-3′-deoxythymidine and that have formula (1), in which The application also relates to a method for preparation of these compounds and to the use of the same for synthesis of 3′-[18F]fluoro-3′-deoxythymidine.