Patent · US Expired

Solution and solid phase synthesis of pyrrolinones and polypyrrolinones

US6891046B2 · kind B2 · utility

0Cited by

3References

15Claims

0Family size

Inventors

Amos B. Smith, III · Yeadon, US
Ralph F. Hirschmann · La Cañada Flintridge, US
Hu Liu · Quincy, US
Hiroyuki Ikumura · Kawanishi, JP

Key dates

Filing date	Apr 25, 2001
Grant date	May 10, 2005
Priority date	—
Expiry date	Jan 31, 2022

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D207/36
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The invention provides a new process for the preparation of polypyrrolinones (I) of various sizes which have found to be useful peptidomimetics. One aspect of the invention is a new process utilizing α-amino-α-substituted-valerolactones as synthons. A second aspect of the invention is a process for the synthesis of polypyrrolinones using solid-phase techniques.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.