Asymmetric synthesis of pregabalin
US6891059B2 · kind B2 · utility
18Cited by
10References
26Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 11, 2001 |
| Grant date | May 10, 2005 |
| Priority date | — |
| Expiry date | Jan 11, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C255/19
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention provides a method of making (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid (pregabalin) or a salt thereof via an asymmetric hydrogenation synthesis. Pregabalin is useful for the treatment and prevention of seizure disorders, pain, and psychotic disorders. The invention also provides intermediates useful in the production of pregabalin.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.