Methods for producing ex vivo models for inflammatory disease and uses thereof
US6893828B2 · kind B2 · utility
2Cited by
2References
4Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Sep 6, 2001 |
| Grant date | May 17, 2005 |
| Priority date | — |
| Expiry date | Feb 7, 2022 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/52
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to methods for inducing a pro-asthma/pro-inflammatory like state in a resident tissue cell, comprising contacting the cell with IL-1β, TNFα or both. Methods are also disclosed for identifying genes that regulate responses to anti-inflammatory drugs, to methods for drug screening, and to methods for identifying genes that correlate with various pro-asthma/pro-inflammatory disease phenotypes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.