Process for preparing virus-inactivated factors 1X and X by membrane chromatography

US6893856B2 · kind B2 · utility

Assignee

• OCTAPHARMA AG · CH

Inventors

• Djuro Josic · Wien, AT
• Ales Strancar · Lilltjärnen, SI

Key dates

• Filing date: May 2, 2002
• Grant date: May 17, 2005
• Expiry date: May 13, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K14/745
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Disclosed is a process for preparing agents containing virus-inactivated vitamin K-dependent plasma components as well as protein C, protein S, factors II, VII, IX and/or X as well as combinations thereof, such as, for example, PPSB preparations, wherein a source containing these components is subjected to a appropriate separation procedures, especially by using membrane-chromatographic methods.