Lithium complexes of N-(1-hydroxymethyl-2,3-dihydroxypropyl)-1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecane, their production and use

US6894151B2 · kind B2 · utility

Assignee

• Shering Corporation · DE

Inventors

• Johannes Platzek · Berlin, DE
• Peter Blaszkiewicz · Berlin, DE
• Orlin Petrov · Berlin, DE
• Holger Hoffmann · Frankfurt am Main, DE

Key dates

• Filing date: Dec 13, 2001
• Grant date: May 17, 2005
• Expiry date: Jun 29, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D257/02
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to crystalline lithium complexes of N-(1-hydroxymethyl-2,3-dihydroxypropyl)-1,4,7-triscarboxymethyl-1,4,7,10 tetraazacyclododecane, their production and the recovery of the salt-free gadolinium complex of N-(1-hydroxymethyl-2,3-dihydroxypropyl)-1,4,7-triscarboxymethyl-1,4,7,10 tetraazacyclododecane from the latter without the use of ion exchangers.