Methods of preparing didesmethylsibutramine and other sibutramine derivatives
US6894189B2 · kind B2 · utility
2Cited by
40References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 20, 2003 |
| Grant date | May 17, 2005 |
| Priority date | — |
| Expiry date | Aug 20, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention encompasses novel methods of preparing sibutramine and sibutramine derivatives, and stereomerically pure sibutramine derivatives in particular. Examples of sibutramine derivatives include, but are not limited to, sibutramine metabolites such as desmethylsibutramine and didesmethylsibutramine. The invention further encompasses novel compounds useful in the synthesis of sibutramine derivatives.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.