Thio semicarbazone and semicarbazone inhibitors of cysteine proteases and methods of their use
US6897240B2 · kind B2 · utility
5Cited by
4References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 8, 2003 |
| Grant date | May 24, 2005 |
| Priority date | — |
| Expiry date | May 8, 2023 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to thio semicarbazone and semicarbazone inhibitors of cysteine proteases and methods of using such compounds to prevent and treat protozoan infections such as trypanosomiasis, malaria and leishmaniasis. The compounds also find use in inhibiting cysteine proteases associated with carcinogenesis, including cathepsins B and L.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.