4-Phenyltetrahydrochinoline utilized as an inhibitor of the cholesterol ester transfer protein

US6897317B2 · kind B2 · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Gunter Schmidt · Houghton, US
• Jurgen Stoltefuss · Haan, DE
• Michael Logers · Wuppertal, DE
• Arndt Brandes · Wuppertal, DE
• Carsten Schmeck · Wuppertal, DE
• Klaus-Dieter Bremm · Recklinghausen, DE
• Hilmar Bischoff · Wuppertal, DE
• Delf Schmidt · Wuppertal, DE

Key dates

• Filing date: Mar 31, 2003
• Grant date: May 24, 2005
• Expiry date: Jul 29, 2023

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/06
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The tetrahydroquinolines can be prepared by condensing appropriately substituted tetrahydroquinoline aldehydes with suitable substances and subsequently varying the substituents present by customary methods. The tetrahydroquinolines are suitable as active compounds in medicaments, in particular in medicaments for the treatment of arteriosclerosis and dyslipidaemias.