Porin B (PorB) as a therapeutic target for prevention and treatment of infection by chlamydia
US6899880B2 · kind B2 · utility
5Cited by
11References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 24, 2002 |
| Grant date | May 31, 2005 |
| Priority date | — |
| Expiry date | May 24, 2022 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention features the use of PorB polypeptide as a therapeutic agent. In specific embodiment the invention features a chlamydial vaccine based on a PorB polypeptide, as well as methods for induction of a protective immune response against infection by Chlamydia and Chlamydiophila. The invention further features methods for identifying agents that affect PorB function such as in transport of α-ketoglutarate and which are effective as anti-chlamydial chemotherapeutic agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.