Method for the production of ω-aminoalkylsulphonic acids

US6900350B2 · kind B2 · utility

Assignee

• RASCHIG GMBH · DE

Inventors

• Volker Schaefer · Ludwigshafen, DE
• Wolfgang Knoll · Mainz, DE
• Alexander Schmitt · Mountain View, US
• Christoph Huettner · Weinheim, DE

Key dates

• Filing date: Apr 27, 2001
• Grant date: May 31, 2005
• Expiry date: Apr 27, 2021

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C303/02
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to a method for the production of ω-aminoalkylsulphonic acids of general formula (I), where R1 and R2=optionally substituted alkyl groups with 1 20 C atoms and n=a whole number from 2 6, whereby an amine of formula (II), where R1 and R2 have the above meanings is reacted with an alkyl dihalide of formula (III), where n has the above meaning and X1 and X2=chlorine or bromine, with addition of alkali hydroxide at a pH of 8 10. The pH is then adjusted to a value of 0 1, by addition of a hydrohalic acid and excess alkyl dihalide is separated off, before the reaction solution is adjusted to a pH of 6 7.5 with alkali liquor, alkali sulphite is added and the product (I) formed at elevated temperate.