Chemokine receptor antagonist and cyclosporin in combined therapy
US6902728B1 · kind B1 · utility
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16Claims
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Assignee
Inventors
Key dates
| Filing date | Sep 16, 1999 |
| Grant date | Jun 7, 2005 |
| Priority date | — |
| Expiry date | Sep 16, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P37/06
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The use of a chemokine receptor antagonist together with a cyclosporin to produce a pharmaceutical composition for treating or preventing rejection of transplanted organs, tissues or cells is herein disclosed. Said pharmaceutical compositions for the simultaneous, sepatate or sequential use of its active ingredients for the above specified therapy are also disclosed and claimed. In particular, the use of Met-RANTES together with cyclosporin A to produce a pharmaceutical composition for the treatment of renal allograft transplant rejection is experimentally shown.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.