Piperazinyl-substituted pyridylalkane, alkene and alkine carboxamides

US6903118B1 · kind B1 · utility

Assignee

• Klinge Pharma GmbH · DE

Inventors

• Elfi Biedermann · Vaterstetten, DE
• Max Hasmann · Schwanau, DE
• Roland Loser · Feldafing, DE
• Benno Rattel · Munich, DE
• Friedemann Reiter · Putzbrunn, DE
• Barbara Schein · Neufahrn, DE
• Klaus Seibel · Gräfelfing, DE
• Klaus Vogt · Munich, DE
• Katja Wosikowski · Poing, DE
• Isabel Schemainda · Munich, DE

Key dates

• Filing date: Jun 16, 2000
• Grant date: Jun 7, 2005
• Expiry date: Jun 16, 2020

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07F9/65583
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to new piperazinyl-substituted pyridylalkane, alkene, and alkine acid amides substituted with saturated or one or several-fold unsaturated hydrocarbon residue in the carboxylic acid group according to the general formula (I) as well as methods for the production of these compounds, medicaments containing these and their production as well as their therapeutic use, especially as cytostatic agents and immunosuppressive agents, for example in the treatment or prevention of various types of tumors and control of immune reactions such as autoimmune diseases.