1-Aryl-2-N-, S- or O-substituted benzimidazole derivatives, their use for the production of pharmaceutical agents as well as pharmaceutical preparations that contain these derivatives

US6903126B2 · kind B2 · utility

Assignee

• SCHERING CORPORATION · US

Inventors

• Thorsten Blume · Schildow, DE
• Wolfgang Halfbrodt · Berlin, DE
• Joachim Kuhnke · Leverkusen, DE
• Ursula Mönning · Mölln, DE
• Herbert Schneider · Berlin, DE

Key dates

• Filing date: Jul 9, 2002
• Grant date: Jun 7, 2005
• Expiry date: Jul 9, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D235/30
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to novel benzimidazole derivatives with general formula I, whereby radicals R1, R2, R3, A, B, Y and Z have the meanings that are indicated in the description and the claims, the use of these compounds for the production of a pharmaceutical agent for treatment and prevention of diseases associated with microglia activation as well as pharmaceutical preparations that contain these compounds