Crosslinked amide derivatives of hyaluronic acid and manufacturing method thereof
US6903199B2 · kind B2 · utility
80Cited by
5References
19Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 10, 2001 |
| Grant date | Jun 7, 2005 |
| Priority date | — |
| Expiry date | Oct 10, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P41/00
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
The present invention relates to water-insoluble, crosslinked amide derivatives of hyaluronic acid and manufacturing method thereof, where the amide derivatives of hyaluronic acid are characterized by crosslinking, of polymer or oligomer having two or more amine groups, with hyaluronic acid or its hyaluronate salts through amidation reaction. The water-insoluble, crosslinked amide derivatives of hyaluronic acid according to the present invention may be diversely used for prevention of adhesion after surgical operation, correction of facial wrinkles, dermal augmentation, tissue engineering, osteoarthritic viscosupplement etc.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.