Methods of screening compounds useful for prevention of infection or pathogenicity

US6905670B2 · kind B2 · utility

Assignee

• The General Hospital Corporation · US

Inventors

• Frederick M. Ausubel · Newton, US
• Stephen B. Calderwood · Wellesley, US
• Eleftherios Mylonakis · Providence, US
• Andrew Diener · Cambridge, US
• Julia Plotnikova · Quincy, US
• Costi Sifri · Quincy, US
• Laurence Rahme · Brookline, US
• Man-Wah Tan · Somerville, US
• Gary Ruvkun · Newton, US
• Georg Jander · Ithaca, US
• Jacqueline E. Heard · Webster Groves, US

Key dates

• Filing date: May 22, 2002
• Grant date: Jun 14, 2005
• Expiry date: Oct 25, 2022

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2333/43534
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Screening procedures are disclosed for identifying compounds useful for inhibiting fungal infection or pathogenicity. Methods are also disclosed for identifying fungal pathogenic virulence factors.