Patent · US Expired

Conjugate of a tissue non-specific alkaline phosphatase and dextran, process for its production and use thereof

US6905689B2 · kind B2 · utility

30Cited by

5References

9Claims

0Family size

Assignee

Roche Diagnostics Operations, Inc. · US

Inventors

Bernd Schneidinger · Starnberg, DE
Thomas Meier · Cherbourg, FR
Rainer Schmuck · Benediktbeuern, DE
Zhixin Shao

Key dates

Filing date	Jul 21, 2003
Grant date	Jun 14, 2005
Priority date	—
Expiry date	Dec 9, 2023

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q1/42
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

A conjugate of a tissue non-specific alkaline phosphatase (tns-AP) and dextran which can be obtained by reacting unglycosylated tns-AP with activated dextran by incubation in aqueous solution, stopping the reaction and isolating the conjugate from the solution. The conjugate obtained in this manner is suitable as a standard for the determination of alkaline phosphatase.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.