Portable pathogen detection system

US6905885B2 · kind B2 · utility

Assignee

• The Regents of the University of California · US

Inventors

• Billy Colston · Livermore, US
• Matthew J. Everett · Livermore, US
• Fred P. Milanovich · Lafayette, US
• Steve Brown · Livermore, US
• Kodumudi Vendateswaran · Livermore, US
• Jonathan Simon · Castro Valley, US

Key dates

• Filing date: Jun 12, 2001
• Grant date: Jun 14, 2005
• Expiry date: Jun 12, 2021

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N33/54313
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A portable pathogen detection system that accomplishes on-site multiplex detection of targets in biological samples. The system includes: microbead specific reagents, incubation/mixing chambers, a disposable microbead capture substrate, and an optical measurement and decoding arrangement. The basis of this system is a highly flexible Liquid Array that utilizes optically encoded microbeads as the templates for biological assays. Target biological samples are optically labeled and captured on the microbeads, which are in turn captured on an ordered array or disordered array disposable capture substrate and then optically read.