N-type calcium channel antagonists for the treatment of pain

US6906193B2 · kind B2 · utility

Assignee

• ASTRAZENECA AB · SE

Inventors

• Glen Ernst · Bear, US
• Marc Chapdelaine · Wilmington, US
• Dannielle Kissel · Boothwyn, US
• Greg A. Hostetler · Newark, US
• John McCauley · Wilmington, US

Key dates

• Filing date: Oct 31, 2001
• Grant date: Jun 14, 2005
• Expiry date: Jan 4, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D221/18
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Compounds useful for the treatment of pain in accord with the following structural diagram, wherein R1, R2, R3, R4 and R5 are any of a number of groups as defined in the specification, A and D are as defined in the specification, and pharmaceutical compositions and methods of treatment utilising such compounds.