Antipicornaviral compounds, their preparation and use
US6906198B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 5, 1999 |
| Grant date | Jun 14, 2005 |
| Priority date | — |
| Expiry date | Jan 5, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K5/0205
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Peptido and peptidomimetic compounds of the formula: wherein the formula variables are as defined in the disclosure, advantageously inhibit or block the biological activity of the picornaviral 3C protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with one or more picornaviruses, such as RVP. Intermediates and synthetic methods for preparing such compounds are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.