Patent · US Expired

Antipicornaviral compounds, their preparation and use

US6906198B1 · kind B1 · utility

1Cited by
1References
5Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 5, 1999
Grant dateJun 14, 2005
Priority date
Expiry dateJan 5, 2019

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K5/0205
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Peptido and peptidomimetic compounds of the formula: wherein the formula variables are as defined in the disclosure, advantageously inhibit or block the biological activity of the picornaviral 3C protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with one or more picornaviruses, such as RVP. Intermediates and synthetic methods for preparing such compounds are also provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.