Raised surface assay plate

US6908760B2 · kind B2 · utility

Assignee

• Transform Pharmaceuticals, Inc. · US

Inventors

• Michael J. Cima · Winchester, US
• Wendy Lewis · Watertown, US
• Javier Gonzalez-Zugasti · Billerica, US
• J Richard Gyory · Sudbury, US
• Anthony Lemmo · Mission Viejo, US
• Julie Monagle · Watertown, US

Key dates

• Filing date: May 16, 2003
• Grant date: Jun 21, 2005
• Expiry date: May 16, 2023

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B01L2300/0829
• WIPO field: Chemical engineering
• WIPO sector: Chemistry

Abstract

The assay plate includes a substrate having an substrate surface and at least one raised pad extending from the substrate surface. The raised pad includes a substantially planar sample receiving surface configured for holding a sample thereon for in-situ experimentation. The sample receiving surface preferably has at least one sharp edge at the junction between a sidewall coupling the sample receiving surface to the substrate surface. The sample receiving surface is preferably a circle, oval, square, rectangle, triangle, pentagon, hexagon, or octagon shape that is sized to hold a predetermined volume of the sample. A method of using the above described assay plate is also provided. Once a raised pad extending from a substrate is formed, a sample is deposited on the raised pad. Experiments are subsequently performed using the sample on the raised pad.