Tricyclic compounds and their uses as antiarrhythmic antifibrillatory and defibrillatory agents
US6908915B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 27, 2000 |
| Grant date | Jun 21, 2005 |
| Priority date | — |
| Expiry date | Dec 25, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D243/38
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A compound having a general formula (II) wherein R1 is saturated or unsaturated alkyl, amino-alcohol, diamino, cycloalkyl, and C(═O)(CH2)nNR′R″, (CH2)nCHOHCH2NR′R″, wherein n is an integer, RQ, RT, R′, and R″ are each independently a hydrogen, halogen, hydroxyl, saturated, unsaturated, aliphatic, or branched alkyl, substituted or unsubstituted (CH2)m-(hetero)aryl, and sulfonylamide; q and r are each an integer independently selected from 1-4; and pharmaceutically acceptable salts thereof, and the new therapeutic uses thereof and similar compounds as defibrillating, and/or anti-fibrillatory, and/or anti-arrhythmic and/or anti-ischemic drugs.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.