Methods of treating neoplasia with combination of target-cell specific adenovirus, chemotherapy and radiation
US6911200B2 · kind B2 · utility
14Cited by
7References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 21, 2001 |
| Grant date | Jun 28, 2005 |
| Priority date | — |
| Expiry date | Mar 21, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2840/203
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides methods of treating neoplasia using combinations of target cell-specific replication competent adenoviral vectors and chemotherapy, radiation therapy or combinations thereof. The adenoviral vectors are target cell-specific for the particular type of neoplasia for which treatment is necessary and the combination with the chemotherapy and/or radiation leads to synergistic treatment over existing adenoviral therapy or traditional chemotherapy and radiation therapy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.