Patent · US Expired

Controlled release bead, a method of producing the same and multiple unit formulation comprising it

US6911217B1 · kind B1 · utility

83Cited by

2References

24Claims

0Family size

Assignee

Pharmacia AB · SE

Inventors

Torkel Gren · Uppsala, SE
Anders Ringberg · Stockholm, SE
Martin Wikberg · Lindome, SE
Randy J. Wald · Bend, US

Key dates

Filing date	Nov 11, 1999
Grant date	Jun 28, 2005
Priority date	—
Expiry date	Nov 11, 2019

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P13/10
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A controlled release bead comprises: (i) a core unit of a substantially water-soluble or water-swellable inert material; (ii) a first layer on the core unit of a substantially water-insoluble polymer; (iii) a second layer covering the first layer and containing an active ingredient; and (iv) a third layer of polymer on the second layer effective for controlled release of the active ingredient, wherein the first layer is adapted to control water penetration into the core. A method of producing the controlled release bead is also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.