Methods of modulating serine/threonine protein kinase function with quinazoline-based compounds
US6911446B2 · kind B2 · utility
22Cited by
9References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 26, 2001 |
| Grant date | Jun 28, 2005 |
| Priority date | — |
| Expiry date | Apr 28, 2022 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/91215
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention is directed in part towards methods of modulating the function of serine/threonine protein kinases with quinazoline-based compounds. The methods incorporate cells that express a serine/threonine protein kinase, such as RAF. In addition, the invention describes methods of preventing and treating serine/threonine protein kinase-related abnormal conditions in organisms with a compound identified by the invention. Furthermore, the invention pertains to quinazoline compounds and pharmaceutical compositions comprising these compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.