Pyrimidine acyclonucleoside derivatives, preparation method and use thereof
US6911450B1 · kind B1 · utility
Assignees
Inventor
Key dates
| Filing date | Jan 25, 2002 |
| Grant date | Jun 28, 2005 |
| Priority date | — |
| Expiry date | Jan 25, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/513
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to a compound having general formula (I): wherein n is equal to 3; R1 is an ethyl or isopropyl group; each of the R2 groups is independently of each other a hydrogen atom, a C1-C3 alkyl group or a halogen atom; one of the R3 and R4 groups represents a hydrogen atom while the other of the R3 and R4 groups represents an OH or OR5 group, where R5 can be a C2-C7 acyl group, an alkyl(C1-C6)animo-carbonyl group, an aralkyl(C1-C6)aminocarbonyl optionally substituted on the aryl, an arylcarbonyl group optionally substituted or a heteroarylaminocarbonyl group. Said compound is particularly suitable as an antiviral agent and especially as an anti-HIV-1 agent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.