Osteoblast-specific mitogens and drugs containing such compounds

US6911553B1 · kind B1 · utility

Assignee

• Roche Diagnostics GMBH · DE

Inventors

• Angelika Esswein · Büttelborn, DE
• Lothar Kling · Mannheim, DE

Key dates

• Filing date: Sep 29, 2000
• Grant date: Jun 28, 2005
• Expiry date: Sep 29, 2020

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07F9/091
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention is directed to compounds of formula (I) wherein R1 alkyl, alkenyl or alkynyl having from 6 to 24 carbon atoms; n=0-12; X=oxygen or NH; and the physiologically safe salts, esters, optically active forms, racemates and derivatives thereof which can be metabolized in vivo to yield compounds of general formula (I), methods of preparing same, and drugs containing said compounds, for treating bone metabolic disorders.