Methods of screening for B cell activity modulators
US6913882B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Dec 21, 2000 |
| Grant date | Jul 5, 2005 |
| Priority date | — |
| Expiry date | Dec 21, 2020 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/10
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention provides for the identification of all genes, whether known or novel, which are differentially expressed within and among B cells, making possible the characterization of their temporal regulation and function in the B cell response and/or in B cell mediated disorders. Expression profiles, nucleic acids and proteins are provided for differing states of B cells, including resting, naive, activated, tolerant and immunosuppressed B cells. The present invention makes possible the identification and characterization of targets useful in prognosis, diagnosis, monitoring, rational drug design, and/or therapeutic intervention of immune system disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.