Patent · US Expired

Macrocyclic NS-3 serine protease inhibitors of hepatitis C virus comprising alkyl and aryl alanine P2 moieties

US6914122B2 · kind B2 · utility

47Cited by
8References
36Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 17, 2001
Grant dateJul 5, 2005
Priority date
Expiry dateApr 25, 2022

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K38/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention discloses novel macrocyclic compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such macrocycles as well as methods of using them to treat disorders associated with the HCV protease.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.