Methods and compositions for expressing polynucleotides specifically in smooth muscle cells in vivo
US6914136B2 · kind B2 · utility
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28Claims
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Assignee
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Key dates
| Filing date | Jan 24, 2002 |
| Grant date | Jul 5, 2005 |
| Priority date | — |
| Expiry date | Jan 24, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2830/85
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention generally relates to promoters, enhancers and other regulatory elements of smooth muscle cells (“SMC”). The invention more particularly relates to methods for the targeted knockout, or over-expression, of genes of interest within smooth muscle cells or within a subtype of smooth muscle cells. The invention further relates to methods of conferring polynucleotide expression in vivo specifically in smooth muscle cells or in subtypes of smooth muscle cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.