Photoreduction method for hemoglobin-vesicle
US6916303B2 · kind B2 · utility
1Cited by
3References
5Claims
0Family size
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Key dates
| Filing date | Feb 12, 2002 |
| Grant date | Jul 12, 2005 |
| Priority date | — |
| Expiry date | Sep 29, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P9/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method and an apparatus for regenerating an oxygen-binding ability by reducing the methemoglobin contained in hemoglobin-vesicle by light irradiation. This method includes adding electron donors such as amino acids, saccharides, alcohols, and/or flavin derivatives in appropriate amounts to the inner aqueous phase of the hemoglobin-vesicle, applying light to the vesicle when the content of methemoglobin increases as a result of oxidation of hemoglobin, thereby reducing the metohemoglobin. In this manner, the oxygen-binding ability is recovered, thereby maintaining the function of the hemoglobin-vesicle.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.