Patent · US Expired

Protein crystallography prescreen kit

US6916455B2 · kind B2 · utility

9Cited by

3References

12Claims

0Family size

Assignee

The Regents of the University of California · US

Inventors

Brent W. Segelke · San Ramon, US
Heike Krupka · Livermore, US
Bernhard Rupp · Eppingen, DE

Key dates

Filing date	Aug 14, 2002
Grant date	Jul 12, 2005
Priority date	—
Expiry date	Oct 24, 2023

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10T117/1024
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

A kit for prescreening protein concentration for crystallization includes a multiplicity of vials, a multiplicity of pre-selected reagents, and a multiplicity of sample plates. The reagents and a corresponding multiplicity of samples of the protein in solutions of varying concentrations are placed on sample plates. The sample plates containing the reagents and samples are incubated. After incubation the sample plates are examined to determine which of the sample concentrations are too low and which the sample concentrations are too high. The sample concentrations that are optimal for protein crystallization are selected and used.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.