Process for producing glycine
US6916638B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 27, 2000 |
| Grant date | Jul 12, 2005 |
| Priority date | — |
| Expiry date | May 23, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P13/04
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Disclosed is a method for producing glycine, which comprises subjecting an aqueous solution of glycinonitrile to a hydrolysis reaction in a hydrolysis reaction system under the action of a microbial enzyme, thereby converting the glycinonitrile to glycine while by-producing ammonia, wherein the hydrolysis reaction system contains at least one organic impurity compound inhibiting the microbial enzyme, wherein the organic impurity compound has a molecular weight of 95 or more and contains at least one member selected from the group consisting of a nitrile group, a carboxyl group, an amide group, an amino group, a hydroxyl group and a trimethyleneamine structure, and wherein the hydrolysis reaction is performed under conditions wherein, during the hydrolysis reaction, the content of the organic impurity compound inhibiting the microbial enzyme in the hydrolysis reaction system is maintained at a level of 10% by weight or less, based on the weight of the hydrolysis reaction system.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.