Process for preparing pyridine-substituted amino ketal derivatives

US6916934B2 · kind B2 · utility

Assignee

• Aventis Pharma Deutschland GmbH · DE

Inventors

• Hans-Wolfram Flemming · Usingen, DE
• Gerhard Korb · Großkrotzenburg, DE
• Juergen Mueller-Lehar · Weinolsheim, DE
• Walter Weber · Lorsch, DE

Key dates

• Filing date: Jan 26, 2004
• Grant date: Jul 12, 2005
• Expiry date: Feb 21, 2024

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D213/51
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention relates to an efficient process for preparing derivatives of 1-(pyridinyl)-1,1-dialkoxy-2-aminoethane of the formula (I), with which compounds of the formula (I) can be prepared in high purity and yield and in the form of the free base without isolating the acetylpyridine oxime of the formula (XI) which is a critical product from a safety point of view as a solid.