Methods and compositions for enhancing the delivery of a nucleic acid to a cell
US6919208B2 · kind B2 · utility
16Cited by
0References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 9, 2001 |
| Grant date | Jul 19, 2005 |
| Priority date | — |
| Expiry date | Mar 7, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to methods and compositions useful for enhancing the efficiency of delivery of a nucleic acid to a cell. Preferably the cell is a mammalian cell. The method comprises providing to a cell an agent capable of enhancing the cytoskeletal permissiveness of the cell for transfection. The method also comprises providing to the cell a nucleic acid delivery system for the transfection of the cell, whereby the efficiency of delivery of a nucleic acid to the cell is enhanced. Compositions and kits for enhancing the efficiency of delivery of a nucleic acid to a cell are also included
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.