Pharmaceutical formulations comprising paclitaxel, derivatives, and pharmaceutically acceptable salts thereof
US6919370B2 · kind B2 · utility
16Cited by
36References
28Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Nov 20, 2001 |
| Grant date | Jul 19, 2005 |
| Priority date | — |
| Expiry date | Nov 20, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/26
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention concerns paclitaxel solubilizers and formulations thereof with a high propensity to dissolve paclitaxel. The formulations of the invention reduce or obviate the need for the disadvantageous excipient Cremophor® EL. The formulations of the invention are useful for administering paclitaxel, its derivatives, or pharmaceutically acceptable salts or such derivatives to patients in need thereof. The formulations of the invention are suitable for parenteral, oral, local, or transdermal administration to mammals including humans, particularly for intravenous delivery.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.